Sequence Detail

ID/Version

O70303 Q91X39 (UniProt | EBI)

Last sequence update: 2002-03-27
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Lipid transferase CIDEB {ECO:0000305};AltName: Full=Cell death activator CIDE-B {ECO:0000303|PubMed:9564035};AltName: Full=Cell death-inducing DFFA-like effector B {ECO:0000303|PubMed:9564035};

Provider

SWISS-PROT

Sequence

Polypeptide 219 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	29	99	3	4

Sequence references in MGI

J:47647 Inohara N, et al., CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. EMBO J. 1998 May 1;17(9):2526-33
J:126556 Li JZ, et al., Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes. 2007 Oct;56(10):2523-32
J:146648 Ye J, et al., Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab. 2009 Feb;9(2):177-90
J:285677 Su L, et al., Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. EMBO J. 2019 Apr 15;38(8)
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:317940 Xu W, et al., Differential Roles of Cell Death-inducing DNA Fragmentation Factor-alpha-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes. J Biol Chem. 2016 Feb 26;291(9):4282-93
J:334007 Tiwari S, et al., CideB protein is required for the biogenesis of very low density lipoprotein (VLDL) transport vesicle. J Biol Chem. 2013 Feb 15;288(7):5157-65