Sequence Detail

ID/Version

O88342 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=WD repeat-containing protein 1;AltName: Full=Actin-interacting protein 1; Short=AIP1;

Provider

SWISS-PROT

Sequence

Polypeptide 606 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wdr1	WD repeat domain 1	41	109	3	26

Sequence references in MGI

J:53288 Adler HJ, et al., A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein. Genomics. 1999 Feb 15;56(1):59-69
J:134092 Kile BT, et al., Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia. Blood. 2007 Oct 1;110(7):2371-80
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:211364 Yuan B, et al., A Cardiomyocyte-Specific Wdr1 Knockout Demonstrates Essential Functional Roles for Actin Disassembly during Myocardial Growth and Maintenance in Mice. Am J Pathol. 2014 Jul;184(7):1967-80
J:233664 Luxenburg C, et al., Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity. Nat Cell Biol. 2015 May;17(5):592-604
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89