Sequence Detail

ID/Version

O88536 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Formyl peptide receptor 2;AltName: Full=Formylpeptide receptor-related sequence 2;AltName: Full=Lipoxin A4 receptor-like protein;AltName: Full=N-formylpeptide receptor-like 2;

Provider

SWISS-PROT

Sequence

Polypeptide 351 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fpr2	formyl peptide receptor 2	33	96	10	16

Sequence references in MGI

J:49567 Gao JL, et al., Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse. Genomics. 1998 Jul 15;51(2):270-6
J:57614 Hartt JK, et al., N-formylpeptides induce two distinct concentration optima for mouse neutrophil chemotaxis by differential interaction with two N-formylpeptide receptor (FPR) subtypes. Molecular characterization of FPR2, a second mouse neutrophil FPR. J Exp Med. 1999 Sep 6;190(5):741-7
J:78957 Vaughn MW, et al., Identification, cloning, and functional characterization of a murine lipoxin a4 receptor homologue gene. J Immunol. 2002 Sep 15;169(6):3363-9
J:99050 Kurosaka K, et al., Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant. J Immunol. 2005 May 15;174(10):6257-65
J:143655 Gao JL, et al., F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor. J Immunol. 2007 Feb 1;178(3):1450-6
J:149471 Riviere S, et al., Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors. Nature. 2009 May 28;459(7246):574-7
J:150065 Liberles SD, et al., Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9842-7
J:345533 Park MY, et al., FAM19A5, a brain-specific chemokine, inhibits RANKL-induced osteoclast formation through formyl peptide receptor 2. Sci Rep. 2017 Nov 14;7(1):15575