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Sequence Detail
ID/Version
O88623 Q6X4T9 Q8VD74 Q6X4U1 Q9JJ87 (UniProt | EBI) Last sequence update: 2022-12-14
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Ubiquitin carboxyl-terminal hydrolase 2 {ECO:0000305}; EC=3.4.19.12;AltName: Full=41 kDa ubiquitin-specific protease;AltName: Full=Deubiquitinating enzyme 2;AltName: Full=Ubiquitin thioesterase 2;AltName: Full=Ubiquitin-specific-proc
Provider SWISS-PROT
Sequence
Polypeptide 619 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Usp2 ubiquitin specific peptidase 2 41 109 4 14
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108694 Gousseva N, et al., Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69. Gene Expr. 2003;11(3-4):163-79
J:215857 Yang Y, et al., Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2. Biol Open. 2012 Aug 15;1(8):789-801
J:243462 Pouly D, et al., USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level. PLoS One. 2016;11(1):e0145155
J:295456 Yang Y, et al., USP2 regulates the intracellular localization of PER1 and circadian gene expression. J Biol Rhythms. 2014 Aug;29(4):243-56

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory