ID/Version |
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Sequence description from provider |
RecName: Full=Epithelial membrane protein 2; Short=EMP-2;AltName: Full=Protein XMP; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
172
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:47934
Ben-Porath I, et al., Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encoding membrane proteins related to Pmp22. Genomics. 1998 May 1;49(3):443-7
J:91398 Wadehra M, et al., The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins. Mol Biol Cell. 2004 May;15(5):2073-83 J:103508 Wadehra M, et al., Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium. Dev Biol. 2005 Nov 15;287(2):336-45 J:109419 Wadehra M, et al., Knockdown of the tetraspan protein epithelial membrane protein-2 inhibits implantation in the mouse. Dev Biol. 2006 Apr 15;292(2):430-41 J:124656 Forbes A, et al., The Tetraspan Protein EMP2 Regulates Expression of Caveolin-1. J Biol Chem. 2007 Sep 7;282(36):26542-51 J:215657 Wadehra M, et al., The tetraspan protein EMP2 increases surface expression of class I major histocompatibility complex proteins and susceptibility to CTL-mediated cell death. Clin Immunol. 2003 May;107(2):129-36 J:215661 Wadehra M, et al., The tetraspan protein epithelial membrane protein-2 interacts with beta1 integrins and regulates adhesion. J Biol Chem. 2002 Oct 25;277(43):41094-100 J:215886 Wadehra M, et al., Steroid hormone regulation of EMP2 expression and localization in the endometrium. Reprod Biol Endocrinol. 2008;6:15 J:243365 Williams CJ, et al., Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency. J Pathol. 2017 Jun;242(2):246-259 J:293323 Lin WC, et al., Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace. J Clin Invest. 2020 Jan 2;130(1):157-170 J:319835 Liu Y, et al., Loss of Emp2 compromises cardiogenic differentiation in mouse embryonic stem cells. Biochem Biophys Res Commun. 2019 Mar 26;511(1):173-178 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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