Sequence Detail

ID/Version

O88700 O88198 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=RecQ-like DNA helicase BLM; EC=5.6.2.4 {ECO:0000269|PubMed:9655940};AltName: Full=Bloom syndrome protein homolog; Short=mBLM;AltName: Full=DNA 3'-5' helicase BLM {ECO:0000305};AltName: Full=RecQ helicase homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 1416 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Blm	Bloom syndrome, RecQ like helicase	134	105	3	70

Sequence references in MGI

J:48817 Seki T, et al., cDNA cloning of mouse BLM gene, the homologue to human Bloom's syndrome gene, which is highly expressed in the testis at the mRNA level. Biochim Biophys Acta. 1998 Jul 9;1398(3):377-81
J:51306 Bahr A, et al., Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein. Oncogene. 1998 Nov 19;17(20):2565-71
J:235782 Braun J, et al., The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis. PLoS One. 2016;11(3):e0152278
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296112 Zhao B, et al., Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex. Cell Res. 2018 Jan;28(1):69-89