Sequence Detail

ID/Version

O88838 Q8CBA5 Q91Z15 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=SPRY domain-containing SOCS box protein 2; Short=SSB-2;AltName: Full=Gene-rich cluster protein C9;

Provider

SWISS-PROT

Sequence

Polypeptide 264 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spsb2	splA/ryanodine receptor domain and SOCS box containing 2	14	96	3	9

Sequence references in MGI

J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:162874 Kuang Z, et al., The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation. J Cell Biol. 2010 Jul 12;190(1):129-41
J:204643 Filippakopoulos P, et al., Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. J Mol Biol. 2010 Aug 20;401(3):389-402
J:245316 Masters SL, et al., The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues. Nat Struct Mol Biol. 2006 Jan;13(1):77-84