Sequence Detail

ID/Version

O88987 Q497M9 (UniProt | EBI)

Last sequence update: 2011-06-28
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=A-kinase anchor protein 3 {ECO:0000305}; Short=AKAP-3 {ECO:0000305};AltName: Full=A-kinase anchor protein 110 kDa {ECO:0000303|PubMed:10319321}; Short=AKAP 110 {ECO:0000303|PubMed:10319321};AltName: Full=Protein kinase A-anch

Provider

SWISS-PROT

Sequence

Polypeptide 864 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Akap3	A kinase anchor protein 3	21	98	2	5

Sequence references in MGI

J:54430 Vijayaraghavan S, et al., Isolation and molecular characterization of AKAP110, a novel, sperm-specific protein kinase A-anchoring protein. Mol Endocrinol. 1999 May;13(5):705-17
J:69494 Carr DW, et al., Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA. J Biol Chem. 2001 May 18;276(20):17332-8
J:284173 Xu K, et al., Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility. Development. 2020 Jan 22;147(2):dev181057
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:345053 Wang Y, et al., Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice. J Genet Genomics. 2023 Sep 13;
J:352418 Yu W, et al., STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in Spermiogenesis. Mol Cell Proteomics. 2023 Jun;22(6):100564