About   Help   FAQ
Sequence Detail
ID/Version
O89090 Q62251 Q64167 O89087 (UniProt | EBI) Last sequence update: 2005-06-21
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Transcription factor Sp1;AltName: Full=Specificity protein 1 {ECO:0000303|PubMed:27918959};
Provider SWISS-PROT
Sequence
Polypeptide 784 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sp1 trans-acting transcription factor 1 90 135 3 257
Sequence references in MGI J:29083 Persengiev SP, et al., An alternatively spliced form of the transcription factor Sp1 containing only a single glutamine-rich transactivation domain. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9107-11
J:44873 Chestier A, et al., Difference in the genomic organizations of the related transcription factors Sp1 and Krox-20; possible evolutionary significance. DNA Seq. 1992;2(5):325-7
J:48065 Yajima S, et al., Sp family transcription factors regulate expression of rat D2 dopamine receptor gene. DNA Cell Biol. 1998 May;17(5):471-9
J:172494 Shetty S, et al., Transcriptional autorepression of Msx1 gene is mediated by interactions of Msx1 protein with a multi-protein transcriptional complex containing TATA-binding protein, Sp1 and cAMP-response-element-binding protein-binding protein (CBP/p300). Biochem J. 1999 May 1;339(Pt 3):751-8
J:211323 Xiao J, et al., Transcription factor NF-Y is a functional regulator of the transcription of core clock gene Bmal1. J Biol Chem. 2013 Nov 1;288(44):31930-6
J:261059 Chuang JY, et al., Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury. Redox Biol. 2017 Apr;11:135-143
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory