Sequence Detail

ID/Version

P05202 O09188 Q3TIP6 Q5HZH5 Q3UD91 (UniProt | EBI)

Last sequence update: 1987-08-13
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Aspartate aminotransferase, mitochondrial; Short=mAspAT; EC=2.6.1.1 {ECO:0000250|UniProtKB:P00507}; EC=2.6.1.7 {ECO:0000250|UniProtKB:P00507};AltName: Full=Fatty acid-binding protein; Short=FABP-1;AltName: Ful

Provider

SWISS-PROT

Sequence

Polypeptide 430 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Got2	glutamatic-oxaloacetic transaminase 2, mitochondrial	48	101	4	14

Sequence references in MGI

J:23932 Obaru K, et al., Cloning and sequence analysis of mRNA for mouse aspartate aminotransferase isoenzymes [published erratum appears in J Biol Chem 1987 Apr 15;262(11):5431]. J Biol Chem. 1986 Dec 25;261(36):16976-83
J:29508 Tsuzuki T, et al., Structural organization of the mouse mitochondrial aspartate aminotransferase gene. J Mol Biol. 1987 Nov 5;198(1):21-31
J:67270 Bradbury MW, et al., Mitochondrial aspartate aminotransferase: direction of a single protein with two distinct functions to two subcellular sites does not require alternative splicing of the mRNA. Biochem J. 2000 Feb 1;345 Pt 3:423-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:291216 van Karnebeek CDM, et al., Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy. Am J Hum Genet. 2019 Sep 5;105(3):534-548
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87