Sequence Detail

ID/Version

P05627 (UniProt | EBI)

Last sequence update: 1989-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Transcription factor Jun {ECO:0000305};AltName: Full=AH119;AltName: Full=Activator protein 1; Short=AP1;AltName: Full=Proto-oncogene c-Jun;AltName: Full=Transcription factor AP-1 subunit Jun {ECO:0000305};AltName: Full=V-jun avian sa

Provider

SWISS-PROT

Sequence

Polypeptide 334 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Jun	jun proto-oncogene	130	142	3	21

Sequence references in MGI

J:9296 Ryseck RP, et al., Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts. Nature. 1988 Aug 11;334(6182):535-7
J:15672 Zerial M, et al., The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity. EMBO J. 1989 Mar;8(3):805-13
J:36299 Ryder K, et al., Induction of protooncogene c-jun by serum growth factors. Proc Natl Acad Sci U S A. 1988 Nov;85(22):8464-7
J:37009 Lamph WW, et al., Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature. 1988 Aug 18;334(6183):629-31
J:73693 Jung DJ, et al., Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors. J Biol Chem. 2002 Jan 11;277(2):1229-34
J:100058 Oukka M, et al., Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. J Exp Med. 2004 Jan 5;199(1):15-24
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:173145 Davies CC, et al., Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation. Nat Cell Biol. 2010 Oct;12(10):963-72
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:254428 Vierbuchen T, et al., AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection. Mol Cell. 2017 Dec 21;68(6):1067-1082.e12
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89