Sequence Detail

ID/Version

P07214 (UniProt | EBI)

Last sequence update: 1988-04-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=SPARC;AltName: Full=Basement-membrane protein 40; Short=BM-40;AltName: Full=Osteonectin; Short=ON;AltName: Full=Secreted protein acidic and rich in cysteine;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 302 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sparc	secreted acidic cysteine rich glycoprotein	38	136	3	179

Sequence references in MGI

J:8388 Mason IJ, et al., Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000. EMBO J. 1986 Jul;5(7):1465-72
J:9287 McVey JH, et al., Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region. J Biol Chem. 1988 Aug 15;263(23):11111-6
J:240593 Engel J, et al., Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues. Biochemistry. 1987 Nov 3;26(22):6958-65
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89