Sequence Detail

ID/Version

P07901 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Heat shock protein HSP 90-alpha {ECO:0000305}; EC=3.6.4.10 {ECO:0000250|UniProtKB:P07900};AltName: Full=Heat shock 86 kDa; Short=HSP 86; Short=HSP86;AltName: Full=Tumor-specific transplantation 86 kDa antigen;

Provider

SWISS-PROT

Sequence

Polypeptide 733 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	176	114	4	73

Sequence references in MGI

J:9666 Moore SK, et al., Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins. J Biol Chem. 1989 Apr 5;264(10):5343-51
J:9749 Hoffmann T, et al., Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens. Gene. 1988 Dec 30;74(2):491-501
J:11471 Moore SK, et al., Mapping of the mouse 86-kDa heat-shock protein expressed gene (Hsp86-1) on chromosome 12 and related genes on chromosomes 3, 4, 9, and 11. Genomics. 1991 Aug;10(4):1019-29
J:30948 Ullrich SJ, et al., A mouse tumor-specific transplantation antigen is a heat shock-related protein. Proc Natl Acad Sci U S A. 1986 May;83(10):3121-5
J:74637 Davies TH, et al., A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. J Biol Chem. 2002 Feb 15;277(7):4597-600
J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:180208 Erez A, et al., Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Dec;17(12):1619-26
J:185047 Sarkar AA, et al., Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme. J Cell Biol. 2012 Mar 19;196(6):789-800
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:230400 Stewart S, et al., Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization. Mol Cell Biol. 1999 Aug;19(8):5523-34
J:247279 Okabe T, et al., REV-ERBalpha influences the stability and nuclear localization of the glucocorticoid receptor. J Cell Sci. 2016 Nov 01;129(21):4143-4154
J:259136 Woodford MR, et al., Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients. EMBO J. 2017 Dec 15;36(24):3650-3665
J:276383 Krzemien-Ojak L, et al., Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein Hsp90. J Cell Biochem. 2017 Feb;118(2):420-429
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89