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Sequence Detail
ID/Version
P08113 P11427 (UniProt | EBI) Last sequence update: 1990-04-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Endoplasmin;AltName: Full=94 kDa glucose-regulated protein; Short=GRP-94;AltName: Full=Endoplasmic reticulum resident protein 99 {ECO:0000303|PubMed:3036833}; Short=ERp99 {ECO:0000303|PubMed:3036833};AltName: Full=Heat shock
Provider SWISS-PROT
Sequence
Polypeptide 802 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Hsp90b1 heat shock protein 90, beta (Grp94), member 1 45 119 4 30
Sequence references in MGI J:17217 Qu D, et al., Analysis of the structure and synthesis of GRP94, an abundant stress protein of the endoplasmic reticulum. DNA Cell Biol. 1994 Feb;13(2):117-24
J:17607 Mazzarella RA, et al., ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp90) and the 94-kDa glucose regulated protein (GRP94). J Biol Chem. 1987 Jun 25;262(18):8875-83
J:20303 Srivastava PK, et al., 5'-structural analysis of genes encoding polymorphic antigens of chemically induced tumors. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3807-11
J:24534 Smith MJ, et al., Isolation and identification of partial cDNA clones for endoplasmin, the major glycoprotein of mammalian endoplasmic reticulum. J Mol Biol. 1987 Mar 20;194(2):345-7
J:117281 Timchenko LT, et al., Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver. J Biol Chem. 2006 Oct 27;281(43):32806-19
J:122196 Han JM, et al., Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases. Am J Pathol. 2007 Jun;170(6):2042-54
J:167004 Flach H, et al., Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. Immunity. 2010 Nov 24;33(5):723-35
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:217288 Meunier L, et al., A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol Biol Cell. 2002 Dec;13(12):4456-69
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory