Sequence Detail

ID/Version

P08228 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Superoxide dismutase [Cu-Zn] {ECO:0000305}; EC=1.15.1.1 {ECO:0000250|UniProtKB:P00441};

Provider

SWISS-PROT

Sequence

Polypeptide 154 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sod1	superoxide dismutase 1, soluble	156	133	3	48

Sequence references in MGI

J:9154 Bewley GC, cDNA and deduced amino acid sequence of murine Cu-Zn superoxide dismutase. Nucleic Acids Res. 1988 Mar 25;16(6):2728
J:28106 Benedetto MT, et al., Isolation and analysis of the mouse genomic sequence encoding Cu(2+)-Zn2+ superoxide dismutase. Gene. 1991 Mar 15;99(2):191-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:169268 Seetharaman SV, et al., Structures of mouse SOD1 and human/mouse SOD1 chimeras. Arch Biochem Biophys. 2010 Nov 15;503(2):183-90
J:173797 Wang SK, et al., Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein. Free Radic Biol Med. 2011 Jul 1;51(1):197-204
J:179975 Sasabe J, et al., D-Amino acid oxidase controls motoneuron degeneration through D-serine. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):627-32
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:252623 Kondori NR, et al., Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons. PLoS One. 2017;12(12):e0188912
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89