Sequence Detail

ID/Version

P08680 Q9DCN0 Q64452 (UniProt | EBI)

Last sequence update: 2002-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=5-aminolevulinate synthase, erythroid-specific, mitochondrial; Short=ALAS-E; EC=2.3.1.37 {ECO:0000269|PubMed:3557128, ECO:0000269|PubMed:8268805};AltName: Full=5-aminolevulinic acid synthase 2;AltName: Full=Delta-ALA synthase

Provider

SWISS-PROT

Sequence

Polypeptide 587 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Alas2	aminolevulinic acid synthase 2, erythroid	26	106	3	3

Sequence references in MGI

J:8626 Schoenhaut DS, et al., Nucleotide sequence of mouse 5-aminolevulinic acid synthase cDNA and expression of its gene in hepatic and erythroid tissues. Gene. 1986;48(1):55-63
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:322688 Ferreira GC, et al., Heme biosynthesis in mammalian systems: evidence of a Schiff base linkage between the pyridoxal 5'-phosphate cofactor and a lysine residue in 5-aminolevulinate synthase. Protein Sci. 1993 Nov;2(11):1959-65