Sequence Detail

ID/Version

P09036 Q5M9M3 (UniProt | EBI)

Last sequence update: 1988-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Serine protease inhibitor Kazal-type 1 {ECO:0000312|MGI:MGI:106202};AltName: Full=P12 {ECO:0000303|PubMed:3428272};AltName: Full=Prostatic secretory glycoprotein {ECO:0000303|PubMed:3428272};AltName: Full=Serine protease inhibitor Kazal-type

Provider

SWISS-PROT

Sequence

Polypeptide 80 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spink1	serine peptidase inhibitor, Kazal type 1	17	105	3	11

Sequence references in MGI

J:25070 Mills JS, et al., A secretory protease inhibitor requires androgens for its expression in male sex accessory tissues but is expressed constitutively in pancreas. EMBO J. 1987 Dec 1;6(12):3711-7
J:52102 Chen LY, et al., Developmental profile of a caltrin-like protease inhibitor, P12, in mouse seminal vesicle and characterization of its binding sites on sperm surface. Biol Reprod. 1998 Dec;59(6):1498-505
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104647 Ohmuraya M, et al., Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice. Gastroenterology. 2005 Aug;129(2):696-705
J:185331 Zalazar L, et al., SPINK3 modulates mouse sperm physiology through the reduction of nitric oxide level independently of its trypsin inhibitory activity. Reproduction. 2012 Mar;143(3):281-95