Sequence Detail

ID/Version

P10107 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Annexin A1;AltName: Full=Annexin I;AltName: Full=Annexin-1;AltName: Full=Calpactin II;AltName: Full=Calpactin-2;AltName: Full=Chromobindin-9;AltName: Full=Lipocortin I {ECO:0000303|PubMed:2974946};AltName: Full=Phospholipase A2 inhibitory pr

Provider

SWISS-PROT

Sequence

Polypeptide 346 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Anxa1	annexin A1	127	108	6	11

Sequence references in MGI

J:9543 Sakata T, et al., Mouse lipocortin I cDNA. Nucleic Acids Res. 1988 Dec 23;16(24):11818
J:11326 Horlick KR, et al., Mouse lipocortin I gene structure and chromosomal assignment: gene duplication and the origins of a gene family. Genomics. 1991 Jun;10(2):365-74
J:81498 Hannon R, et al., Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J. 2003 Feb;17(2):253-5
J:87169 Lennon NJ, et al., Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing. J Biol Chem. 2003 Dec 12;278(50):50466-73
J:125876 Reynolds SD, et al., CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway. Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L114-23
J:126333 D'Acquisto F, et al., Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. Eur J Immunol. 2007 Nov;37(11):3131-42
J:142735 Babbin BA, et al., Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J Immunol. 2008 Oct 1;181(7):5035-44
J:182881 Patel DM, et al., Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis. J Cell Sci. 2011 Feb 15;124(Pt 4):578-88
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:220546 Leoni G, et al., Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest. 2015 Mar 2;125(3):1215-27
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89