Sequence Detail

ID/Version

P10126 Q99KU5 Q8BVS8 Q61511 Q6ZWN2 Q8BMB8 (UniProt | EBI)

Last sequence update: 2004-10-25
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Elongation factor 1-alpha 1; Short=EF-1-alpha-1; EC=3.6.5.- {ECO:0000250|UniProtKB:P68104};AltName: Full=Elongation factor Tu; Short=EF-Tu;AltName: Full=Eukaryotic elongation factor 1 A-1; Short=eEF1A-1;

Provider

SWISS-PROT

Sequence

Polypeptide 462 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Eef1a1	eukaryotic translation elongation factor 1 alpha 1	59	100	5	47

Sequence references in MGI

J:9029 Roth WW, et al., Expression of a gene for mouse eucaryotic elongation factor Tu during murine erythroleukemic cell differentiation. Mol Cell Biol. 1987 Nov;7(11):3929-36
J:9546 Lu XA, et al., The complete cDNA sequence of mouse elongation factor 1 alpha (EF 1 alpha) mRNA. Nucleic Acids Res. 1989 Jan 11;17(1):442
J:9558 Reddy NS, et al., Isolation and mapping of a gene for protein synthesis initiation factor 4A and its expression during differentiation of murine erythroleukemia cells. Gene. 1988 Oct 30;70(2):231-43
J:20256 Rao TR, et al., Structure of the amino-terminal end of mammalian elongation factor Tu [published erratum appears in Nucleic Acids Res 1986 Aug 11;14(15):6344]. Nucleic Acids Res. 1986 Mar 11;14(5):2409
J:40501 Whiteheart SW, et al., Murine elongation factor 1 alpha (EF-1 alpha) is posttranslationally modified by novel amide-linked ethanolamine-phosphoglycerol moieties. Addition of ethanolamine-phosphoglycerol to specific glutamic acid residues on EF-1 alpha. J Biol Chem. 1989 Aug 25;264(24):14334-41
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506
J:192650 Li HT, et al., The interaction between interferon-induced protein with tetratricopeptide repeats-1 and eukaryotic elongation factor-1A. Mol Cell Biochem. 2010 Apr;337(1-2):101-10
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:240550 Malecki J, et al., The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Res. 2017 Jan 20;45(8):4370-4389
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89