ID/Version |
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Sequence description from provider |
RecName: Full=Cyclin-dependent kinase 1; Short=CDK1; EC=2.7.11.22 {ECO:0000269|PubMed:36264786}; EC=2.7.11.23 {ECO:0000305|PubMed:2662013};AltName: Full=Cell division control protein 2 homolog {ECO:0000303|PubMed:2208288};AltName: | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
297
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:9854
Cisek LJ, et al., Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2. Nature. 1989 Jun 29;339(6227):679-84
J:10753 Th'ng JP, et al., The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell. 1990 Oct 19;63(2):313-24 J:52474 Jun D, et al., Characterization of the murine cdc2 gene. Mol Cells. 1998 Dec 31;8(6):731-40 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:100155 Aleem E, et al., Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol. 2005 Aug;7(8):831-6 J:101521 Han SJ, et al., Wee1B is an oocyte-specific kinase involved in the control of meiotic arrest in the mouse. Curr Biol. 2005 Sep 20;15(18):1670-6 J:124678 Santamaria D, et al., Cdk1 is sufficient to drive the mammalian cell cycle. Nature. 2007 Aug 16;448(7155):811-5 J:171197 Oh JS, et al., Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes. Science. 2011 Apr 22;332(6028):462-5 J:183245 Mondal G, et al., Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint. Mol Cell. 2012 Mar 9;45(5):680-95 J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30 J:272927 Inaba H, et al., Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase. Biochem Biophys Res Commun. 2018 Apr 6;498(3):544-550 J:279007 Gomez-H L, et al., The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLoS Genet. 2019 Aug;15(8):e1008316 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:331922 Cheng S, et al., Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment. Science. 2022 Oct 21;378(6617):eabq4835 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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