Sequence Detail

ID/Version

P11672 Q3UE34 (UniProt | EBI)

Last sequence update: 1989-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Neutrophil gelatinase-associated lipocalin; Short=NGAL;AltName: Full=Lipocalin-2;AltName: Full=Oncogene 24p3 {ECO:0000303|PubMed:1834059}; Short=24p3 {ECO:0000303|PubMed:2542864};AltName: Full=SV-40-induced 24p3 protein {ECO:

Provider

SWISS-PROT

Sequence

Polypeptide 200 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lcn2	lipocalin 2	44	113	4	18

Sequence references in MGI

J:17361 Flower DR, et al., Mouse oncogene protein 24p3 is a member of the lipocalin protein family. Biochem Biophys Res Commun. 1991 Oct 15;180(1):69-74
J:20468 Hraba-Renevey S, et al., SV40-induced expression of mouse gene 24p3 involves a post-transcriptional mechanism. Oncogene. 1989 May;4(5):601-8
J:33041 Garay-Rojas E, et al., An apparent autocrine mechanism amplifies the dexamethasone- and retinoic acid-induced expression of mouse lipocalin-encoding gene 24p3. Gene. 1996 May 8;170(2):173-80
J:33547 Chu ST, et al., Demonstration of a glycoprotein derived from the 24p3 gene in mouse uterine luminal fluid. Biochem J. 1996 Jun 1;316(Pt 2):545-50
J:95107 Flo TH, et al., Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature. 2004 Dec 16;432(7019):917-21
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106079 Berger T, et al., Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1834-9
J:163023 Devireddy LR, et al., A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production. Cell. 2010 Jun 11;141(6):1006-17
J:163136 Devireddy LR, et al., A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell. 2005 Dec 29;123(7):1293-305
J:270608 Murtha MJ, et al., Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses. J Clin Invest. 2018 Dec 3;128(12):5634-5646
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89