Sequence Detail

ID/Version

P11679 Q61518 Q61519 Q3TKY7 Q61463 Q3TGI1 Q3KQK5 Q3TJE1 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Keratin, type II cytoskeletal 8;AltName: Full=Cytokeratin endo A;AltName: Full=Cytokeratin-8; Short=CK-8;AltName: Full=Keratin-8; Short=K8;AltName: Full=Type-II keratin Kb8;

Provider

SWISS-PROT

Sequence

Polypeptide 490 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Krt8	keratin 8	39	208	5	13

Sequence references in MGI

J:9566 Morita T, et al., Nucleotide sequence of mouse EndoA cytokeratin cDNA reveals polypeptide characteristics of the type-II keratin subfamily. Gene. 1988 Aug 15;68(1):109-17
J:9697 Ouellet T, et al., Complete sequence of the mouse type-II keratin EndoA: its amino-terminal region resembles mitochondrial signal peptides. Gene. 1988 Oct 15;70(1):75-84
J:11466 Tamai Y, et al., Sequence of EndoA gene encoding mouse cytokeratin and its methylation state in the CpG-rich region. Gene. 1991 Aug 15;104(2):169-76
J:49478 Semat A, et al., Sequence analysis of murine cytokeratin endo A (no. 8) cDNA. Evidence for mRNA species initiated upstream of the normal 5' end in PCC4 cells. Differentiation. 1988;37(1):40-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:125625 Zhou Q, et al., Keratin 20 helps maintain intermediate filament organization in intestinal epithelia. Mol Biol Cell. 2003 Jul;14(7):2959-71
J:166791 Menon MB, et al., p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins. J Biol Chem. 2010 Oct 22;285(43):33242-51
J:236209 Szabo S, et al., Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization. J Hepatol. 2015 Jun;62(6):1357-66
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:322687 Bouameur JE, et al., Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure. J Invest Dermatol. 2014 Nov;134(11):2776-2783