Sequence Detail

ID/Version

P11798 Q6ZWN4 Q61284 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Calcium/calmodulin-dependent protein kinase type II subunit alpha; Short=CaM kinase II subunit alpha; Short=CaMK-II subunit alpha; EC=2.7.11.17 {ECO:0000269|PubMed:23502535};

Provider

SWISS-PROT

Sequence

Polypeptide 478 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Camk2a	calcium/calmodulin-dependent protein kinase II alpha	86	114	3	53

Sequence references in MGI

J:9840 Hanley RM, et al., Sequence of the cDNA for the alpha subunit of calmodulin kinase II from mouse brain. Nucleic Acids Res. 1989 May 25;17(10):3992
J:30302 Bayer KU, et al., An alternative, nonkinase product of the brain-specifically expressed Ca2+/calmodulin-dependent kinase II alpha isoform gene in skeletal muscle. Mol Cell Biol. 1996 Jan;16(1):29-36
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:197634 Shonesy BC, et al., CaMKII regulates diacylglycerol lipase-alpha and striatal endocannabinoid signaling. Nat Neurosci. 2013 Apr;16(4):456-63
J:239596 Stephenson JR, et al., A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors. J Neurosci. 2017 Feb 22;37(8):2216-2233
J:240285 Pufall MA, et al., Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science. 2005 Jul 01;309(5731):142-5
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:314561 Vigil FA, et al., Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor. Sci Rep. 2017 Jun 22;7(1):4040