Sequence Detail

ID/Version

P12979 (UniProt | EBI)

Last sequence update: 1992-12-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Myogenin;AltName: Full=MYOD1-related protein;

Provider

SWISS-PROT

Sequence

Polypeptide 224 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Myog	myogenin	69	304	3	14

Sequence references in MGI

J:14059 Nabeshima Y, et al., Myogenin gene disruption results in perinatal lethality because of severe muscle defect [see comments]. Nature. 1993 Aug 5;364(6437):532-5
J:14208 Hasty P, et al., Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene [see comments]. Nature. 1993 Aug 5;364(6437):501-6
J:20949 Smith TH, et al., Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins. J Cell Biol. 1994 Oct;127(1):95-105
J:29010 Edmondson DG, et al., A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program [published erratum appears in Genes Dev 1990 Aug;4(8):1450]. Genes Dev. 1989 May;3(5):628-40
J:32287 Sassoon D, et al., Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis. Nature. 1989 Sep 28;341(6240):303-7
J:37554 Edmondson DG, et al., Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2. Mol Cell Biol. 1992 Sep;12(9):3665-77
J:43313 Fujisawa-Sehara A, et al., Myogenin contains two domains conserved among myogenic factors. J Biol Chem. 1990 Sep 5;265(25):15219-23
J:105925 Knapp JR, et al., Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size. Development. 2006 Feb;133(4):601-10
J:105939 Cao Y, et al., Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters. EMBO J. 2006 Feb 8;25(3):502-11
J:105941 Ohkawa Y, et al., Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1. EMBO J. 2006 Feb 8;25(3):490-501
J:200312 Blais A, et al., An initial blueprint for myogenic differentiation. Genes Dev. 2005 Mar 1;19(5):553-69
J:200498 Macpherson PC, et al., Myogenin regulates denervation-dependent muscle atrophy in mouse soleus muscle. J Cell Biochem. 2011 Aug;112(8):2149-59
J:203388 Liu QC, et al., Comparative expression profiling identifies differential roles for Myogenin and p38alpha MAPK signaling in myogenesis. J Mol Cell Biol. 2012 Dec;4(6):386-97