Sequence Detail

ID/Version

P15499 (UniProt | EBI)

Last sequence update: 1990-04-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Peripherin-2;AltName: Full=Retinal degeneration slow protein;

Provider

SWISS-PROT

Sequence

Polypeptide 346 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prph2	peripherin 2	23	104	4	18

Sequence references in MGI

J:7415 Jansen HG, et al., Development and degeneration of retina in rds mutant mice: electron microscopy. J Comp Neurol. 1984 Mar 20;224(1):71-84
J:9635 Travis GH, et al., Identification of a photoreceptor-specific mRNA encoded by the gene responsible for retinal degeneration slow (rds). Nature. 1989 Mar 2;338(6210):70-3
J:10978 Connell G, et al., Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse. Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):723-6
J:28016 Ma J, et al., Retinal degeneration slow (rds) in mouse results from simple insertion of a t haplotype-specific element into protein-coding exon II. Genomics. 1995 Jul 20;28(2):212-9
J:61888 Clarke G, et al., Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis. Nat Genet. 2000 May;25(1):67-73
J:266419 Zulliger R, et al., Oligomerization of Prph2 and Rom1 is essential for photoreceptor outer segment formation. Hum Mol Genet. 2018 Oct 15;27(20):3507-3518
J:279806 Zulliger R, et al., SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS One. 2015;10(9):e0138508