Sequence Detail

ID/Version

P15539 Q14AB5 Q64661 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cytochrome P450 11B2, mitochondrial;AltName: Full=Aldosterone synthase {ECO:0000250|UniProtKB:P19099}; Short=ALDOS;AltName: Full=Aldosterone-synthesizing enzyme;AltName: Full=CYPXIB2;AltName: Full=Corticosterone 18-monooxygenase, CYP

Provider

SWISS-PROT

Sequence

Polypeptide 500 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2	30	100	5	13

Sequence references in MGI

J:1546 Domalik LJ, et al., Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids. Mol Endocrinol. 1991 Dec;5(12):1853-61
J:9530 Mouw AR, et al., Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase. J Biol Chem. 1989 Jan 15;264(2):1305-9