Sequence Detail

ID/Version

P15920 Q8VHU0 Q3U2X3 Q9JHJ2 A4FU82 (UniProt | EBI)

Last sequence update: 2001-01-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=V-type proton ATPase 116 kDa subunit a 2; Short=V-ATPase 116 kDa subunit a 2;AltName: Full=Immune suppressor factor J6B7; Short=ISF;AltName: Full=Lysosomal H(+)-transporting ATPase V0 subunit a 2;AltName: Full=ShIF;AltName: F

Provider

SWISS-PROT

Sequence

Polypeptide 856 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp6v0a2	ATPase, H+ transporting, lysosomal V0 subunit A2	23	112	3	4

Sequence references in MGI

J:30662 Lee C, et al., Cloning of a cDNA for a T cell produced molecule with a putative immune regulatory role. Mol Immunol. 1990 Nov;27(11):1137-44
J:61083 Nishi T, et al., Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase. J Biol Chem. 2000 Mar 10;275(10):6824-30
J:61380 Toyomura T, et al., Three subunit a isoforms of mouse vacuolar H(+)-ATPase. Preferential expression of the a3 isoform during osteoclast differentiation. J Biol Chem. 2000 Mar 24;275(12):8760-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116421 Hurtado-Lorenzo A, et al., V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006 Feb;8(2):124-36
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89