Sequence Detail

ID/Version

P16092 E9Q2P4 Q01736 Q8CFK8 Q60830 Q61562 Q9QZM7 Q80T10 (UniProt | EBI)

Last sequence update: 1991-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Fibroblast growth factor receptor 1; Short=FGFR-1; Short=bFGF-R-1; EC=2.7.10.1 {ECO:0000250|UniProtKB:P11362};AltName: Full=Basic fibroblast growth factor receptor 1;AltName: Full=MFR;AltName: Full=Proto-oncogene c-Fg

Provider

SWISS-PROT

Sequence

Polypeptide 822 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fgfr1	fibroblast growth factor receptor 1	206	225	4	277

Sequence references in MGI

J:10524 Safran A, et al., The murine flg gene encodes a receptor for fibroblast growth factor. Oncogene. 1990 May;5(5):635-43
J:17074 Reid HH, et al., Two forms of the basic fibroblast growth factor receptor-like mRNA are expressed in the developing mouse brain. Proc Natl Acad Sci U S A. 1990 Feb;87(4):1596-600
J:21860 Jin Y, et al., Cloning and expression of fibroblast growth factor receptor-1 isoforms in the mouse heart: evidence for isoform switching during heart development. J Mol Cell Cardiol. 1994 Nov;26(11):1449-59
J:22015 Harada T, et al., Murine fibroblast growth factor receptor 1 gene generates multiple messenger RNAs containing two open reading frames via alternative splicing. Biochem Biophys Res Commun. 1994 Dec 15;205(2):1057-63
J:22117 Yamaguchi TP, et al., fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 1994 Dec 15;8(24):3032-44
J:22118 Deng CX, et al., Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 1994 Dec 15;8(24):3045-57
J:26802 Kouhara H, et al., Expression cDNA cloning of fibroblast growth factor (FGF) receptor in mouse breast cancer cells: a variant form in FGF-responsive transformed cells. Biochem Biophys Res Commun. 1991 Apr 15;176(1):31-7
J:31506 Mansukhani A, et al., A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF. Proc Natl Acad Sci U S A. 1990 Jun;87(11):4378-82
J:62309 Beer HD, et al., Fibroblast growth factor (FGF) receptor 1-IIIb is a naturally occurring functional receptor for FGFs that is preferentially expressed in the skin and the brain. J Biol Chem. 2000 May 26;275(21):16091-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112631 Haines BP, et al., Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development. Dev Biol. 2006 Sep 1;297(1):14-25
J:117479 Urakawa I, et al., Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature. 2006 Dec 7;444(7120):770-4
J:121336 Ogawa Y, et al., BetaKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7432-7
J:128002 Rizzoti K, et al., SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis. Development. 2007 Oct;134(19):3437-48
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89