Sequence Detail

ID/Version

P16460 (UniProt | EBI)

Last sequence update: 1990-08-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Argininosuccinate synthase {ECO:0000305}; EC=6.3.4.5 {ECO:0000250|UniProtKB:P00966};AltName: Full=Citrulline--aspartate ligase;

Provider

SWISS-PROT

Sequence

Polypeptide 412 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ass1	argininosuccinate synthetase 1	79	99	3	49

Sequence references in MGI

J:11142 Surh LC, et al., Molecular characterization of the murine argininosuccinate synthetase locus. Gene. 1991 Mar 15;99(2):181-9
J:180208 Erez A, et al., Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Dec;17(12):1619-26
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:250437 Lin R, et al., CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis. Mol Cell. 2017 Oct 5;68(1):198-209.e6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89