Sequence Detail

ID/Version

P17426 (UniProt | EBI)

Last sequence update: 1990-08-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=AP-2 complex subunit alpha-1;AltName: Full=100 kDa coated vesicle protein A;AltName: Full=Adaptor protein complex AP-2 subunit alpha-1;AltName: Full=Adaptor-related protein complex 2 subunit alpha-1;AltName: Full=Alpha-adaptin A;AltName: Ful

Provider

SWISS-PROT

Sequence

Polypeptide 977 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ap2a1	adaptor-related protein complex 2, alpha 1 subunit	45	103	3	13

Sequence references in MGI

J:21441 Robinson MS, Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins). J Cell Biol. 1989 Mar;108(3):833-42
J:168194 Uezu A, et al., SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15. J Biol Chem. 2007 Sep 7;282(36):26481-9
J:201438 Marcello E, et al., Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. J Clin Invest. 2013 Jun 3;123(6):2523-38
J:255150 Piccini A, et al., APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development. Cell Rep. 2017 Dec 19;21(12):3596-3611
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89