ID/Version |
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Sequence description from provider |
RecName: Full=AP-2 complex subunit alpha-2 {ECO:0000305};AltName: Full=100 kDa coated vesicle protein C;AltName: Full=Adaptor protein complex AP-2 subunit alpha-2;AltName: Full=Adaptor-related protein complex 2 subunit alpha-2;AltName: Full=Alpha-adaptin | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
938
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:21441
Robinson MS, Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins). J Cell Biol. 1989 Mar;108(3):833-42
J:47962 Jurecic R, et al., Identification and cloning of differentially expressed genes by long-distance differential display. Anal Biochem. 1998 Jun 1;259(2):235-44 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:185432 Umasankar PK, et al., Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol. 2012 May;14(5):488-501 J:188910 Morris SM, et al., Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. Traffic. 2001 Feb;2(2):111-23 J:201438 Marcello E, et al., Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. J Clin Invest. 2013 Jun 3;123(6):2523-38 J:206083 Montagnac G, et al., alphaTAT1 catalyses microtubule acetylation at clathrin-coated pits. Nature. 2013 Oct 24;502(7472):567-70 J:230366 Brett TJ, et al., Accessory protein recruitment motifs in clathrin-mediated endocytosis. Structure. 2002 Jun;10(6):797-809 J:230398 Traub LM, et al., Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8907-12 J:255150 Piccini A, et al., APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development. Cell Rep. 2017 Dec 19;21(12):3596-3611 J:256610 Chang HF, et al., Cytotoxic granule endocytosis depends on the Flower protein. J Cell Biol. 2018 Feb 5;217(2):667-683 J:289084 Kawasaki T, et al., Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha. Biochem J. 2008 Jan 15;409(2):471-9 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:343380 Scheele U, et al., Multiple interactions of auxilin 1 with clathrin and the AP-2 adaptor complex. J Biol Chem. 2001 Sep 28;276(39):36131-8 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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