Sequence Detail

ID/Version

P17742 Q9R137 Q9CWJ5 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Peptidyl-prolyl cis-trans isomerase A; Short=PPIase A; EC=5.2.1.8 {ECO:0000269|PubMed:24429998, ECO:0000305|PubMed:25678563};AltName: Full=Cyclophilin A;AltName: Full=Cyclosporin A-binding protein;AltName: Full=Rotamase A;Alt

Provider

SWISS-PROT

Sequence

Polypeptide 164 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ppia	peptidylprolyl isomerase A	77	105	8	22

Sequence references in MGI

J:10648 Hasel KW, et al., Nucleotide sequence of a cDNA coding for mouse cyclophilin. Nucleic Acids Res. 1990 Jul 11;18(13):4019
J:64523 Colgan J, et al., Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability. Genomics. 2000 Sep 1;68(2):167-78
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110552 Urano Y, et al., Involvement of the mouse Prp19 gene in neuronal/astroglial cell fate decisions. J Biol Chem. 2006 Mar 17;281(11):7498-514
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:292533 Wang L, et al., Cyclophilin A is an important mediator of platelet function by regulating integrin alphaIIbbeta3 bidirectional signalling. Thromb Haemost. 2014 May 5;111(5):873-82
J:292536 Lauranzano E, et al., Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes. Brain. 2015 Apr;138(Pt 4):974-91