Sequence Detail

ID/Version

P18581 Q38RA6 E9QPL9 Q3U3R5 Q3TB99 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Cationic amino acid transporter 2 {ECO:0000305}; Short=CAT-2; Short=CAT2;AltName: Full=20.5;AltName: Full=Low affinity cationic amino acid transporter 2 {ECO:0000303|PubMed:8385111};AltName: Full=Solute carrier family 7 membe

Provider

SWISS-PROT

Sequence

Polypeptide 657 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	40	101	3	14

Sequence references in MGI

J:10562 MacLeod CL, et al., Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor. Mol Cell Biol. 1990 Jul;10(7):3663-74
J:18606 Closs EI, et al., Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver. J Biol Chem. 1993 Apr 5;268(10):7538-44
J:18942 Kavanaugh MP, et al., Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family. J Biol Chem. 1994 Jun 3;269(22):15445-50
J:40643 Closs EI, et al., Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry. 1997 May 27;36(21):6462-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:131710 Yeramian A, et al., Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages. J Immunol. 2006 May 15;176(10):5918-24
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89