Sequence Detail

ID/Version

P19783 Q545A9 (UniProt | EBI)

Last sequence update: 1993-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;AltName: Full=Cytochrome c oxidase polypeptide IV;AltName: Full=Cytochrome c oxidase subunit IV isoform 1; Short=COX IV-1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 169 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cox4i1	cytochrome c oxidase subunit 4I1	18	130	3	3

Sequence references in MGI

J:10828 Grossman LI, et al., Nucleotide sequence of a mouse cDNA for subunit IV of cytochrome c oxidase. Nucleic Acids Res. 1990 Nov 11;18(21):6454
J:11447 Carter RS, et al., Cloning and characterization of the mouse cytochrome c oxidase subunit IV gene. Arch Biochem Biophys. 1991 Jul;288(1):97-106
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:273588 Strub GM, et al., Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration. FASEB J. 2011 Feb;25(2):600-12
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:301602 Li Y, et al., MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nat Commun. 2020 Sep 24;11(1):4837
J:345052 Li J, et al., The immunity-related GTPase IRGC mediates interaction between lipid droplets and mitochondria to facilitate sperm motility. FEBS Lett. 2023 Jun;597(12):1595-1605
J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
J:357966 Vercellino I, et al., Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV. Nature. 2021 Oct;598(7880):364-367