Sequence Detail

ID/Version

P19785 Q9QY52 Q9QY51 Q9JJT5 (UniProt | EBI)

Last sequence update: 1991-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Estrogen receptor; Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 599 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Esr1	estrogen receptor 1 (alpha)	158	152	3	58

Sequence references in MGI

J:28689 White R, et al., Structural organization and expression of the mouse estrogen receptor. Mol Endocrinol. 1987 Oct;1(10):735-44
J:38668 Jiang MS, et al., A subpopulation of estrogen receptors are modified by O-linked N-acetylglucosamine. J Biol Chem. 1997 Jan 24;272(4):2421-8
J:42181 Torchia J, et al., The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function [see comments]. Nature. 1997 Jun 12;387(6634):677-84
J:62059 Zhu Y, et al., Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR. J Biol Chem. 2000 May 5;275(18):13510-6
J:63613 Kos M, et al., Tissue-specific expression of multiple mRNA variants of the mouse estrogen receptor alpha gene. FEBS Lett. 2000 Jul 14;477(1-2):15-20
J:73693 Jung DJ, et al., Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors. J Biol Chem. 2002 Jan 11;277(2):1229-34
J:99324 Chen YH, et al., GAC63, a GRIP1-Dependent Nuclear Receptor Coactivator. Mol Cell Biol. 2005 Jul;25(14):5965-72
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114106 Kurtev V, et al., Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases. J Biol Chem. 2004 Jun 4;279(23):24834-43
J:125396 Li D, et al., Constitutive Coactivator of Peroxisome Proliferator-Activated Receptor (PPAR{gamma}), a Novel Coactivator of PPAR{gamma} that Promotes Adipogenesis. Mol Endocrinol. 2007 Oct;21(10):2320-33
J:157008 Uhlenhaut NH, et al., Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. Cell. 2009 Dec 11;139(6):1130-42
J:182421 Mak HY, et al., Molecular determinants of the estrogen receptor-coactivator interface. Mol Cell Biol. 1999 May;19(5):3895-903
J:239215 Budhram-Mahadeo V, et al., POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element. Mol Cell Biol. 1998 Feb;18(2):1029-41