Sequence Detail

ID/Version

P20108 (UniProt | EBI)

Last sequence update: 1991-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Thioredoxin-dependent peroxide reductase, mitochondrial; EC=1.11.1.24 {ECO:0000269|PubMed:9497357};AltName: Full=Antioxidant protein 1; Short=AOP-1;AltName: Full=PRX III;AltName: Full=Perioredoxin-3;AltName: Full=Protein MER5

Provider

SWISS-PROT

Sequence

Polypeptide 257 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prdx3	peroxiredoxin 3	59	103	3	16

Sequence references in MGI

J:10114 Yamamoto T, et al., Cloning of a housekeeping-type gene (MER5) preferentially expressed in murine erythroleukemia cells. Gene. 1989 Aug 15;80(2):337-43
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:294889 Zhang YG, et al., Featured Article: Accelerated decline of physical strength in peroxiredoxin-3 knockout mice. Exp Biol Med (Maywood). 2016 Jul;241(13):1395-400
J:296117 Cao Y, et al., ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5. Nat Chem Biol. 2019 Dec;15(12):1232-1240