ID/Version |
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Sequence description from provider |
RecName: Full=POU domain, class 5, transcription factor 1;AltName: Full=NF-A3;AltName: Full=Octamer-binding protein 3; Short=Oct-3;AltName: Full=Octamer-binding protein 4; Short=Oct-4;AltName: Full=Octamer-binding transcription factor 3; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
352
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:1910
Okazawa H, et al., The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. EMBO J. 1991 Oct;10(10):2997-3005
J:10293 Okamoto K, et al., A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell. 1990 Feb 9;60(3):461-72 J:10576 Rosner MH, et al., A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature. 1990 Jun 21;345(6277):686-92 J:27203 Scholer HR, et al., New type of POU domain in germ line-specific protein Oct-4. Nature. 1990 Mar 29;344(6265):435-9 J:100846 Maruyama M, et al., Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J Biol Chem. 2005 Jul 1;280(26):24371-9 J:116485 Tsuruzoe S, et al., Inhibition of DNA binding of Sox2 by the SUMO conjugation. Biochem Biophys Res Commun. 2006 Dec 29;351(4):920-6 J:140350 van den Berg DL, et al., Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression. Mol Cell Biol. 2008 Oct;28(19):5986-95 J:161094 Yu HB, et al., Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells. J Biol Chem. 2009 Nov 6;284(45):31327-35 J:163434 Liao B, et al., Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner. Cell Res. 2010 Mar;20(3):332-44 J:195215 Esch D, et al., A unique Oct4 interface is crucial for reprogramming to pluripotency. Nat Cell Biol. 2013 Mar;15(3):295-301 J:255341 Ma H, et al., Zfp322a Regulates mouse ES cell pluripotency and enhances reprogramming efficiency. PLoS Genet. 2014 Feb;10(2):e1004038 J:259122 Bae KB, et al., Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells. Stem Cell Reports. 2017 Dec 12;9(6):2050-2064 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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