Sequence Detail

ID/Version

P20491 (UniProt | EBI)

Last sequence update: 1991-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=High affinity immunoglobulin epsilon receptor subunit gamma;AltName: Full=Fc receptor gamma-chain; Short=FcRgamma;AltName: Full=Fc-epsilon RI-gamma;AltName: Full=IgE Fc receptor subunit gamma; Short=FceRI gamma;Flags: Precurs

Provider

SWISS-PROT

Sequence

Polypeptide 86 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	110	99	4	17

Sequence references in MGI

J:31359 Ra C, et al., Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells. J Biol Chem. 1989 Sep 15;264(26):15323-7
J:40327 Poole A, et al., The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J. 1997 May 1;16(9):2333-41
J:88051 Sakurai D, et al., Fc epsilon RI gamma-ITAM is differentially required for mast cell function in vivo. J Immunol. 2004 Feb 15;172(4):2374-81
J:116120 Mocsai A, et al., Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs. Nat Immunol. 2006 Dec;7(12):1326-33
J:141143 Yamasaki S, et al., Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol. 2008 Oct;9(10):1179-88
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:144525 Hida S, et al., Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol. 2009 Feb;10(2):214-22
J:166868 Enomoto Y, et al., Characterization of leukocyte mono-immunoglobulin-like receptor 7 (LMIR7)/CLM-3 as an activating receptor: its similarities to and differences from LMIR4/CLM-5. J Biol Chem. 2010 Nov 12;285(46):35274-83
J:168200 Sato K, et al., Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses. J Biol Chem. 2006 Dec 15;281(50):38854-66
J:203159 Miyake Y, et al., C-type lectin MCL is an FcRgamma-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor. Immunity. 2013 May 23;38(5):1050-62