Sequence Detail

ID/Version

P21845 Q61962 (UniProt | EBI)

Last sequence update: 1991-08-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Tryptase beta-2; Short=Tryptase-2; EC=3.4.21.59;AltName: Full=Mast cell protease 6; Short=mMCP-6;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 276 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tpsb2	tryptase beta 2	11	103	5	6

Sequence references in MGI

J:11003 Reynolds DS, et al., Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass. J Biol Chem. 1991 Feb 25;266(6):3847-53
J:17707 Reynolds DS, et al., Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases. Proc Natl Acad Sci U S A. 1990 Apr;87(8):3230-4
J:22087 Huang R, et al., Genes for mast-cell serine protease and their molecular evolution. Immunogenetics. 1994;40(6):397-414
J:113235 Abraham D, et al., The expression pattern of three mast cell specific proteases during mouse development. Mol Immunol. 2007 Feb;44(5):732-40
J:124554 Thakurdas SM, et al., The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. J Biol Chem. 2007 Jul 20;282(29):20809-15