Sequence Detail

ID/Version

P21855 A2AIN6 Q64225 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=B-cell differentiation antigen CD72;AltName: Full=Lyb-2;AltName: Full=Lymphocyte antigen 32; Short=Ly-32;AltName: CD_antigen=CD72;

Provider

SWISS-PROT

Sequence

Polypeptide 354 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd72	CD72 antigen	5	97	2	12

Sequence references in MGI

J:1507 Robinson WH, et al., Extensive polymorphism in the extracellular domain of the mouse B cell differentiation antigen Lyb-2/CD72. J Immunol. 1992 Aug 1;149(3):880-6
J:43413 Nakayama E, et al., Sequence of the Lyb-2 B-cell differentiation antigen defines a gene superfamily of receptors with inverted membrane orientation. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1352-6
J:76990 Pan C, et al., CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation. Immunity. 1999 Oct;11(4):495-506
J:237518 Akatsu C, et al., CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP. J Exp Med. 2016 Nov 14;213(12):2691-2706
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:354149 Adachi T, et al., The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. J Immunol. 1998 May 15;160(10):4662-5