Sequence Detail

ID/Version

P22005 Q68G73 (UniProt | EBI)

Last sequence update: 2009-06-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Proenkephalin-A {ECO:0000305};Contains: RecName: Full=Synenkephalin;Contains: RecName: Full=Met-enkephalin; AltName: Full=Opioid growth factor; Short=OGF;Contains: RecName: Full=PENK(114-133) {ECO:0000250|UniProtKB:P04094};Cont

Provider

SWISS-PROT

Sequence

Polypeptide 268 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Penk	preproenkephalin	61	133	4	13

Sequence references in MGI

J:8253 Zurawski G, et al., Activation of mouse T-helper cells induces abundant preproenkephalin mRNA synthesis. Science. 1986 May 9;232(4751):772-5
J:10565 Kilpatrick DL, et al., Transcription of the rat and mouse proenkephalin genes is initiated at distinct sites in spermatogenic and somatic cells. Mol Cell Biol. 1990 Jul;10(7):3717-26
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:322689 Trieu BH, et al., Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid. Science. 2022 Mar 11;375(6585):1177-1182
J:322698 Inturrisi CE, et al., Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5512-4