Sequence Detail

ID/Version

P22599 Q8VC20 Q61283 Q80ZH5 (UniProt | EBI)

Last sequence update: 2005-06-21
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Alpha-1-antitrypsin 1-2; Short=AAT;AltName: Full=Alpha-1 protease inhibitor 2;AltName: Full=Alpha-1-antiproteinase;AltName: Full=Serine protease inhibitor 1-2;AltName: Full=Serine protease inhibitor A1b; Short=Serpin A1b;Flag

Provider

SWISS-PROT

Sequence

Polypeptide 413 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	22	98	9	4

Sequence references in MGI

J:10300 Sifers RN, et al., Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin. Genomics. 1990 Jan;6(1):100-4
J:23546 Borriello F, et al., Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9417-21
J:31321 Paterson T, et al., The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins. Biochem Biophys Res Commun. 1996 Feb 6;219(1):64-9
J:76390 Barbour KW, et al., Functional Diversification During Evolution of the Murine alpha(1)-Proteinase Inhibitor Family: Role of the Hypervariable Reactive Center Loop. Mol Biol Evol. 2002 May;19(5):718-27
J:80096 Barbour KW, et al., The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure. Genomics. 2002 Nov;80(5):515-22
J:82699 Forsyth S, et al., A review and comparison of the murine alpha(1)-antitrypsin and alpha(1)-antichymotrypsin multigene clusters with the human clade A serpins. Genomics. 2003 Mar;81(3):336-45
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89