Sequence Detail

ID/Version

P22724 (UniProt | EBI)

Last sequence update: 1991-08-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Protein Wnt-4;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 351 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wnt4	wingless-type MMTV integration site family, member 4	133	225	3	24

Sequence references in MGI

J:10971 Gavin BJ, et al., Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32
J:21884 Stark K, et al., Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994 Dec 15;372(6507):679-83
J:52554 Vainio S, et al., Female development in mammals is regulated by Wnt-4 signalling. Nature. 1999 Feb 4;397(6718):405-9
J:63226 Tanaka K, et al., The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem. 2000 Jul;267(13):4300-11
J:100575 Carroll TJ, et al., Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92
J:122521 Park JS, et al., Wnt/{beta}-catenin signaling regulates nephron induction during mouse kidney development. Development. 2007 Jul;134(13):2533-9
J:154784 Shan J, et al., Generation of an allele to inactivate Wnt4 gene function conditionally in the mouse. Genesis. 2009 Nov;47(11):782-8
J:226411 Caprioli A, et al., Wnt4 is essential to normal mammalian lung development. Dev Biol. 2015 Oct 15;406(2):222-34