Sequence Detail

ID/Version

P22907 Q3TIV0 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Porphobilinogen deaminase {ECO:0000305}; Short=PBG-D; EC=2.5.1.61 {ECO:0000250|UniProtKB:P08397};AltName: Full=Hydroxymethylbilane synthase; Short=HMBS;AltName: Full=Pre-uroporphyrinogen synthase;

Provider

SWISS-PROT

Sequence

Polypeptide 361 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hmbs	hydroxymethylbilane synthase	23	103	4	14

Sequence references in MGI

J:9974 Beaumont C, et al., The mouse porphobilinogen deaminase gene. Structural organization, sequence, and transcriptional analysis. J Biol Chem. 1989 Sep 5;264(25):14829-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89