Sequence Detail

ID/Version

P23359 Q91XF7 (UniProt | EBI)

Last sequence update: 2002-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Bone morphogenetic protein 7; Short=BMP-7;AltName: Full=Osteogenic protein 1; Short=OP-1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 430 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bmp7	bone morphogenetic protein 7	124	230	4	24

Sequence references in MGI

J:29330 Ozkaynak E, et al., Murine osteogenic protein (OP-1): high levels of mRNA in kidney. Biochem Biophys Res Commun. 1991 Aug 30;179(1):116-23
J:38288 Jena N, et al., BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye. Exp Cell Res. 1997 Jan 10;230(1):28-37
J:86665 Laurikkala J, et al., Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev Biol. 2003 Dec 1;264(1):91-105
J:98379 Zakin L, et al., Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May;132(10):2489-99
J:224205 Segklia A, et al., Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse. PLoS One. 2012;7(3):e34088
J:270227 Arezes J, et al., Erythroferrone inhibits the induction of hepcidin by BMP6. Blood. 2018 Oct 4;132(14):1473-1477