Sequence Detail

ID/Version

P24529 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Tyrosine 3-monooxygenase; EC=1.14.16.2 {ECO:0000250|UniProtKB:P07101};AltName: Full=Tyrosine 3-hydroxylase; Short=TH;

Provider

SWISS-PROT

Sequence

Polypeptide 498 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Th	tyrosine hydroxylase	128	322	3	31

Sequence references in MGI

J:11212 Ichikawa S, et al., Primary structure of mouse tyrosine hydroxylase deduced from its cDNA. Biochem Biophys Res Commun. 1991 May 15;176(3):1610-6
J:24347 Zhou QY, et al., Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature. 1995 Apr 13;374(6523):640-3
J:136786 Ihara M, et al., Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron. 2007 Feb 15;53(4):519-33
J:279052 Nguyen MT, et al., An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. Nat Cell Biol. 2019 Apr;21(4):420-429
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89