Sequence Detail

ID/Version

P25322 (UniProt | EBI)

Last sequence update: 1992-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=G1/S-specific cyclin-D1;

Provider

SWISS-PROT

Sequence

Polypeptide 295 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ccnd1	cyclin D1	90	224	3	25

Sequence references in MGI

J:14776 Matsushime H, et al., Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell. 1991 May 17;65(4):701-13
J:22834 Smith R, et al., Genomic organization of the mouse cyclin D1 gene (Cyl-1). Genomics. 1995 Jan 1;25(1):85-92
J:28743 Poon RY, et al., Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation. Mol Biol Cell. 1995 Sep;6(9):1197-213
J:162977 Barbash O, et al., Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation. Oncogene. 2009 Dec 10;28(49):4317-25
J:184685 Wilson CH, et al., Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation. EMBO J. 2012;31(11):2486-97
J:305884 Maiani E, et al., AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. Nature. 2021 Apr;592(7856):799-803