Sequence Detail

ID/Version

P25916 (UniProt | EBI)

Last sequence update: 1992-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Polycomb complex protein BMI-1;AltName: Full=Polycomb group RING finger protein 4;

Provider

SWISS-PROT

Sequence

Polypeptide 324 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bmi1	Bmi1 polycomb ring finger oncogene	72	126	5	22

Sequence references in MGI

J:11213 van Lohuizen M, et al., Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging [see comments]. Cell. 1991 May 31;65(5):737-52
J:11214 Haupt Y, et al., Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice [see comments]. Cell. 1991 May 31;65(5):753-63
J:104662 Cao R, et al., Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell. 2005 Dec 22;20(6):845-54
J:119024 Buchwald G, et al., Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b. EMBO J. 2006 Jun 7;25(11):2465-74
J:198334 Negishi M, et al., A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1. PLoS One. 2010;5(8):e12373