Sequence Detail

ID/Version

P26041 Q8BSN4 Q3UL28 B1AX70 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Moesin {ECO:0000303|PubMed:1429901};AltName: Full=Membrane-organizing extension spike protein;

Provider

SWISS-PROT

Sequence

Polypeptide 577 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Msn	moesin	86	108	4	24

Sequence references in MGI

J:2811 Sato N, et al., A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites. J Cell Sci. 1992 Sep;103(Pt 1):131-43
J:52936 Doi Y, et al., Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout. J Biol Chem. 1999 Jan 22;274(4):2315-21
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:189837 Hirata T, et al., Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis. Int Immunol. 2012 Nov;24(11):705-17
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:251018 Satooka H, et al., The ERM Protein Moesin Regulates CD8(+) Regulatory T Cell Homeostasis and Self-Tolerance. J Immunol. 2017 Nov 15;199(10):3418-3426
J:255604 Yonemura S, et al., Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J Cell Biol. 1998 Feb 23;140(4):885-95
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89