Sequence Detail

ID/Version

P26048 (UniProt | EBI)

Last sequence update: 1992-05-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-2 {ECO:0000303|PubMed:11528422};AltName: Full=GABA(A) receptor subunit alpha-2 {ECO:0000303|PubMed:11528422}; Short=GABAAR subunit alpha-2 {ECO:0000303|PubMed:27129275};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 451 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gabra2	gamma-aminobutyric acid type A receptor subunit alpha 2	41	107	3	20

Sequence references in MGI

J:2118 Wang JB, et al., The alpha 1, alpha 2, and alpha 3 subunits of GABAA receptors: comparison in seizure-prone and -resistant mice and during development. J Mol Neurosci. 1992;3(4):177-84
J:254795 Davenport EC, et al., An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Cell Rep. 2017 Oct 3;21(1):70-83
J:281261 Brown LE, et al., gamma-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains. J Biol Chem. 2016 Jul 1;291(27):13926-42
J:281687 Han W, et al., Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions. Science. 2019 Oct 11;366(6462):246-250